419 was another route that used to serve Philadelphia before it was cut back to Camden.
Indirectly related, but in Center City Philadelphia, there's a block-long vacant property at 8th and Market. I'm surprised nobody has ever thought about relocating the Greyhound Terminal from it's current (cramped and very sketchy) location at 11-Filbert. It makes it a lot easier for buses to navigate in and out from 8-Market compared to 11-Filbert, much easier connections to Market-Frankford, Broad-Ridge Spur and PATCO, and by potentially having all NJT buses terminate at 8-Market, you eliminate that time consuming loop along Market, Broad and Vine Streets that tends to foul up the South Jersey locals, especially the 400.