These are just random ideas that just popped into my head:
B33 operates weekdays only between Kings County Hospital and Red Hook-IKEA.
via Clarkson Av, Parkside Av, Prospect Park SW, 15 St, 8 Av SB-9 Av NB, 9 St, Lorraine St and into IKEA.
B27/B32* will operate at all times between East NY-Broadway Junction and Bay Ridge-Shore Rd.
via ENY Ave, Clarkson Av, Parkside Av, and Fort Hamilton Pkwy up to 92 St, then via 4 Av to Shore Rd.
*B27 LCL/B32 LTD weekday service.
B21 operates all times between Coney Island-Stillwell Av and Downtown Brooklyn.
via Ocean Pkwy, Prospect Park SW, and 4 Ave.
M105/M105 LTD* operates between Port Authority Bus Terminal, Manhattan and Cotsco-39 St/1 Ave, Brooklyn. via 7 Av (SB), 8 Av (NB), Manhattan Bridge, and 3 Ave (BK).
*M105 LTD runs between 7AM and 7PM. (Customers should use the M20 for local service. M105 runs local in Brooklyn.) All other times, M105 makes all stops.
S67 operates all times between St. George Ferry Terminal and Bensonhurst-Bay Pkwy/Shore Rd.
via Bay St, Verrazano Bridge, 86 St and Cropsey/Bath Avs.
B64 operates at all times between Sea Gate-W 37 St and Bay Ridge-Shore Rd, replacing the B74.
via Mermaid Av, Stillwell Av Station Loop, Bath Av, 13 Av and Bay Ridge Ave.